As interprofessional education (IPE) grows, more health professions programs have begun promoting it in their accreditation standards. A frequent challenge of large universities is how to include the large set of diverse students in their foundational offerings. A potential way would be to implement an online IPE asynchronous experience with an optional synchronous discussion. The purpose of this study was to: 1) describe implementation of that approach at a large multi-campus university; 2) explore the associations between IPE activities and students' reported level of usefulness; and 3) provide recommendations for online IPE experiences.An IPE Module was developed that had 4 sequential online learning activities. After finishing the module, participants completed a self-administered questionnaire that included questions about demographics, retrospective pre and post assessment of key IPE concepts, and rating of the usefulness of the learning based on the module activities.1,017 participants, representing 8 different health professional programs, completed the survey. The numbers of students were evenly distributed, with dentistry representing the highest number (21%), and most participants were first-year students (71.9%). The learning activities "reading posts/messages of colleagues from other professions" and "watching the video" were reported useful or very useful by 77.4% and 71.4% of participants, respectively. The self-reflection writing activity (67.1%) and the "6-word message" (59.4%) were rated as useful or very useful by over half of participants.Most participants reported that the learning activities in the online asynchronous IPE module were useful or very useful in achieving the learning objectives. Thus, an introductory experience based on an online program combining both asynchronous and decentralized optional synchronous instruction might be a viable method of delivering foundational IPE information.