Co-downregulation of cell adhesion proteins alpha- and beta-catenins, p120CTN, E-cadherin, and CD44 in prostatic adenocarcinomas
Abstract
Cell adhesion molecule expression has been linked to disease outcome in prostatic adenocarcinomas (PACs). We evaluated the coordinated expression of catenin-related proteins, E-cadherin, N-cadherin, and CD44s in PACs. Archival sections from 112 PACs were immunostained by an automated method (Ventana …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
humans
pubmed abstract
nih
national institutes of health
national library of medicine
prognosis
male
Comparative Study
DNA
fluorescent antibody technique
adenocarcinoma / secondary
ploidies
phosphoproteins / metabolism
trans-activators*
indirect
beta catenin
neoplasm proteins / metabolism*
prostatic neoplasms / metabolism*
prostatic neoplasms / pathology
adenocarcinoma / metabolism*
cadherins / metabolism
neoplasm / analysis
pmid:11521230
doi:10.1053/hupa.2001.26463
b v kallakury
c e sheehan
j s ross
catenins
cell adhesion molecules / metabolism*
cytoskeletal proteins / metabolism
down-regulation*
hyaluronan receptors / metabolism
image cytometry
alpha catenin
Citation
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272691
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