Signalling scaffolds and local organization of cellular behaviour - Nature Reviews Molecular Cell Biology

Signalling scaffolds and local organization of cellular behaviour - Nature Reviews Molecular Cell Biology

Lorene K. Langeberg;John D. Scott;Lorene K. Langeberg;John D. Scott;
Nature Reviews Molecular Cell Biology 2015 Vol. 16 pp. 232-244
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langeberg2015naturesignalling

Abstract

Recent technical advances have shown that scaffold proteins can hold members of a signal transduction cascade in place, focus enzyme activity at a particular site of action and/or provide a structural platform for the recruitment of signal transduction and signal termination enzymes.

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