CRISPR Diagnosis and Therapeutics with Single Base Pair Precision

CRISPR Diagnosis and Therapeutics with Single Base Pair Precision

Lee SH;Park YH;Jin YB;Kim SU;Hur JK;;
trends in molecular medicine 2020 Vol. 26 pp. -
250
sh2020trendscrispr

Abstract

Clustered regularly interspaced short palindromic repeats, or CRISPR, has been widely accepted as a versatile genome editing tool with significant potential for medical application. Reliable allele specificity is one of the most critical elements for successful application of this technology to deve …

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