CRISPR Diagnosis and Therapeutics with Single Base Pair Precision
Lee SH;Park YH;Jin YB;Kim SU;Hur JK;;
trends in molecular medicine2020Vol. 26pp. -
250
sh2020trendscrispr
Abstract
Clustered regularly interspaced short palindromic repeats, or CRISPR, has been widely accepted as a versatile genome editing tool with significant potential for medical application. Reliable allele specificity is one of the most critical elements for successful application of this technology to deve …