Rapid diagnosis of pneumococcal meningitis: implications for treatment and measuring disease burden
Abstract
ICT for pneumococcal antigen in CSF is 100% sensitive and specific in diagnosing pyogenic pneumococcal meningitis and can detect approximately 30% more pneumococcal meningitis cases than with culture alone. The simplicity of the test procedure and the longevity of CSF antigen detection suggest the p …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
Child
Infant
Comparative Study
preschool
Antigens
sensitivity and specificity
Evaluation Study
Polymerase Chain Reaction / methods
chromatography / methods
pneumococcal / diagnosis*
pmid:16371872
doi:10.1097/01.inf.0000190030.75892.78
samir k saha
gary l darmstadt
davidson h hamer
bacterial* / cerebrospinal fluid
bacterial* / urine
bacterial typing techniques
cerebrospinal fluid / microbiology
culture media
immunoassay
latex fixation tests
meningitis
pneumococcal / microbiology
streptococcus pneumoniae / genetics
streptococcus pneumoniae / isolation & purification*
time factors
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Citation
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110572
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