Synthesis of the Sex Pheromone of the Tea Tussock Moth Based on a Resource Chemistry Strategy

Synthesis of the Sex Pheromone of the Tea Tussock Moth Based on a Resource Chemistry Strategy

Zhang, Hong-Li;Sun, Zhi-Feng;Zhou, Lu-Nan;Liu, Lu;Zhang, Tao;Du, Zhen-Ting;
molecules 2018 Vol. 23 pp. 1347-
167
zhang2018synthesismolecules

Abstract

Synthesis of the sex pheromone of the tea tussock moth in 33% overall yield over 10 steps was achieved. Moreover, the chiral pool concept was applied in the asymmetric synthesis. The synthesis used a chemical available on a large-scale from recycling of wastewater from the steroid industry. The carbon skeleton was constructed using the C4+C5+C8 strategy. Based on this strategy, the original chiral center was totally retained.

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