Chemical Constituents from Stem Bark and Roots of Clausena anisata

Chemical Constituents from Stem Bark and Roots of Clausena anisata

Dongo, Etienne;Mpondo, Theophile Ngando;White, Robert L.;Songue, Jules Lobe;Kouam, ;
molecules 2012 Vol. 17 pp. 13673-13686
346
dongo2012chemicalmolecules

Abstract

Phytochemical investigations on the stem bark and roots of the tropical shrub Clausena anisata led to the isolation and characterization three carbazole alkaloids: girinimbine, murrayamine-A and ekeberginine; two peptide derivatives: aurantiamide acetate and N-benzoyl-l-phenylalaninyl-N-benzoyl-l-phenylalaninate; and a mixture of two phytosterols: sitosterol and stigmasterol. The structures of these compounds were established by nuclear magnetic resonance (1H-NMR, 13C-NMR, COSY, HSQC, HMQC, HMBC and NOESY) spectroscopy and electrospray ionization mass spectrometry (MS).

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