Resveratrol Maintains Lipid Metabolism Homeostasis via One of the Mechanisms Associated with the Key Circadian Regulator Bmal1

Resveratrol Maintains Lipid Metabolism Homeostasis via One of the Mechanisms Associated with the Key Circadian Regulator Bmal1

Jing Li;Liping Wei;Caicai Zhao;Junyi Li;Zhigang Liu;Min Zhang;Yutang Wang;Li, Jing;Wei, Liping;Zhao, Caicai;Li, Junyi;Liu, Zhigang;Zhang, Min;Wang, Yutang and
molecules 1970 Vol. 24 pp. 2916-
310
jing1970resveratrolmolecules

Abstract

Resveratrol (RES) possesses anti-inflammatory and anti-oxidant activities, and it can prevent liver lipid metabolism disorders in obese and diabetic individuals. This study elucidated the mechanisms of brain and muscle Arnt-like protein-1 (Bmal1) in the protective effects of RES against liver lipid metabolism disorders. The results indicated that RES ameliorated free fatty acid (FFA)-induced (oleic acid (OA): palmitic acid (PA)

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