Abstract To allow doctors to monitor the physical parameters of the patient’s body in real time and to understand the changes in the patient’s condition in time, the medical remote monitoring system based on the Internet of Things was studied. From the perspective of practical application of hospital wards, a medical health monitoring system was designed with the help of CC2430 microcontroller, human information sensor, and microelectronic and modern wireless communication technology. In addition, a sensor node circuit and a coordinator node circuit for collecting medical signals were designed. Meanwhile, the software of wireless sensor network was designed. Finally, the online debugging of each system module was combined with hardware and software. The experimental result proved that the network node was reliable and the data transmission was accurate. It is concluded that the medical monitoring system basically meets the design requirements of this paper.