4E-T-bound mRNAs are stored in a silenced and deadenylated form
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4E-T-bound mRNAs are stored in a silenced and deadenylated form

Felix Räsch, Ramona Weber, Elisa Izaurralde, Cátia Igreja;Felix Räsch;Ramona Weber;Elisa Izaurralde;Cátia Igreja;
genes & development 2020 Vol. 34 pp. 847-
103
igreja2020genes4e-t-bound

Abstract

Human 4E-T is an eIF4E-binding protein (4E-BP) present in processing (P)-bodies that represses translation and regulates decay of mRNAs destabilized by AU-rich elements and microRNAs (miRNAs). However, the underlying regulatory mechanisms are still unclear. ...

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DOI:
10.1101/gad.336073.119
URL:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC726314...

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