IL-10 mediates susceptibility to Leishmania donovani infection
Abstract
Human visceral leishmaniasis (VL) results in a severe and potentially fatal systemic disease, accompanied by cellular immune depression. The production of IL-10 correlates with ongoing disease and it has been suggested that the cellular immune depression that accompanies active disease may be due to …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
Mice
Inbred C57BL
animals
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
u.s. gov't
female
P.H.S.
Inbred BALB C
interferon-gamma / biosynthesis
nitric oxide / biosynthesis
leishmaniasis
visceral / immunology*
nitric oxide synthase type ii
pmid:11592059
doi:10.1002/1521-4141(2001010)31:10<2848::aid-immu2848>3.0.co;2-t
m l murphy
u wille
j p farrell
granuloma / enzymology
interleukin-10 / physiology*
interleukin-12 / physiology
leishmania donovani*
liver diseases / enzymology
nitric oxide synthase / biosynthesis
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273307
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