Activation of cAMP and mitogen responsive genes relies on a common nuclear factor
Abstract
A number of signalling pathways stimulate transcription of target genes through nuclear factors whose activities are primarily regulated by phosphorylation. Cyclic AMP regulates the expression of numerous genes, for example, through the protein kinase-A (PKA)-mediated phosphorylation of transcriptio …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
genetic
Mice
animals
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
u.s. gov't
amino acid sequence
P.H.S.
signal transduction*
Genes
3T3 Cells
Nuclear Proteins / metabolism*
Transcription Factors / metabolism*
Molecular Sequence Data
Gene Expression Regulation*
Promoter Regions
transcription
blotting
western
hela cells
rabbits
phosphorylation
reporter
creb-binding protein
trans-activators*
cyclic amp response element-binding protein / metabolism
proto-oncogene proteins c-jun / genetics
Nuclear Proteins / immunology
m montminy
serine / metabolism
pmid:8028671
doi:10.1038/370226a0
j arias
a s alberts
cyclic amp / metabolism*
mitogens / metabolism*
transcription factors / immunology
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273044
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