Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock
Abstract
Effective antimicrobial administration within the first hour of documented hypotension was associated with increased survival to hospital discharge in adult patients with septic shock. Despite a progressive increase in mortality rate with increasing delays, only 50% of septic shock patients received …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
adult
female
male
middle aged
united states / epidemiology
Comparative Study
Multicenter Study
Retrospective Studies
follow-up studies
time factors
odds ratio
prevalence
anti-infective agents / therapeutic use*
shock
septic / complications
septic / mortality*
survival rate / trends
pmid:16625125
doi:10.1097/01.ccm.0000217961.75225.e9
anand kumar
daniel roberts
mary cheang
hospital mortality / trends
hypotension / epidemiology*
hypotension / etiology
manitoba / epidemiology
patient discharge / statistics & numerical data
patient discharge / trends
septic / drug therapy
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271713
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