Modulation of cellular apoptotic potential: contributions to oncogenesis
Abstract
The importance of apoptosis as a natural means to eliminate unwanted or damaged cells has been realized over the past decade. Many components required to exercise programmed cell death have been identified and shown to pre-exist in most, if not all, cells. Such ubiquity requires that apoptosis be ti …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
review
animals
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
drosophila melanogaster / physiology
phosphoinositide-3 kinase inhibitors
neoplasms / therapy
caenorhabditis elegans / genetics
drosophila melanogaster / genetics
signal transduction* / genetics
neoplasms / pathology*
apoptosis / physiology*
phosphatidylinositol 3-kinases / metabolism
pten phosphohydrolase
proto-oncogene proteins c-akt
proto-oncogene proteins / metabolism*
drosophila proteins
protein-serine-threonine kinases*
phosphoric monoester hydrolases / metabolism
neoplasms / enzymology*
pmid:10557100
doi:10.1038/sj.onc.1203126
v stambolic
t w mak
j r woodgett
caenorhabditis elegans / enzymology
caenorhabditis elegans / physiology
cell survival / physiology
drosophila melanogaster / enzymology
phosphatidylinositol 3-kinases / genetics
tumor suppressor proteins*
Citation
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271700
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