Nkx3.1, a murine homolog of Ddrosophila bagpipe, regulates epithelial ductal branching and proliferation of the prostate and palatine glands
Abstract
Nkx3.1 is a homeobox gene related to Drosophila bagpipe. Nkx3.1 is an early marker of the sclerotome and a subset of vascular smooth muscle cells, and at later stages, this gene is expressed in the prostate, palatine glands, kidney, and restricted regions of the central nervous system. In the presen …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
Mice
Inbred C57BL
Drosophila
animals
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
u.s. gov't
male
P.H.S.
Genes
Knockout
transcription factors / genetics*
insect proteins / genetics
inbred strains
transcription factors / physiology
homozygote
genetic linkage
drosophila proteins*
chromosome mapping*
kidney / embryology
repressor proteins / genetics
trans-activators / genetics
transcription factors / deficiency
tumor suppressor*
homeodomain proteins / physiology
homeodomain proteins / genetics*
pmid:11002344
doi:10.1002/1097-0177(2000)9999:99993.3.co;2-5
m tanaka
i komuro
s izumo
palate / embryology*
prostate / embryology*
prostate / growth & development
seminal vesicles / embryology
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271653
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