The two components of the tropical overturning circulation, the meridional Hadley circulation (HC) and the zonal Walker circulation (WC), are key to the re-distribution of moisture, heat and mass in the atmosphere. The mid-Pliocene Warm Period (mPWP; ∼ 3.3–3 Ma) is considered a very rough analogue of near-term future climate change, yet changes to the tropical overturning circulations in the mPWP are poorly understood. Here, climate model simulations from the Pliocene Model Intercomparison Project (PlioMIP) are analyzed to show that the tropical overturning circulations in the mPWP were weaker than preindustrial circulations, just as they are projected to be in future climate change. The weakening HC response is consistent with future projections, and its strength is strongly related to the meridional gradient of sea surface warming between the tropical and subtropical oceans. The weakening of the WC is less robust in PlioMIP than in future projections, largely due to inter-model variations in simulated warming of the tropical Indian Ocean (TIO). When the TIO warms faster (slower) than the tropical mean, local upper tropospheric divergence increases (decreases) and the WC weakens less (more). These results provide strong evidence that changes to the tropical overturning circulation in the mPWP and future climate are primarily controlled by zonal (WC) and meridional (HC) gradients in tropical–subtropical sea surface temperatures.