Single carrier block transmission (SCBT) system has become one of the most popular modulation systems due to its low peak-to-average power ratio (PAPR), and it is gradually considered to be used for uplink wireless communication systems. In this paper, a low complexity partial parallel interference cancellation (PIC) with maximum ratio combining (MRC) technology is proposed to use for receiver to combat the intersymbol interference (ISI) problem over multipath fading channel. With the aid of MRC scheme, the proposed partial PIC technique can effectively perform the interference cancellation and acquire the benefit of time diversity gain. Finally, the proposed system can be extended to use for multiple antenna systems to provide excellent performance. Simulation results reveal that the proposed low complexity partial PIC-MRC SIMO system can provide robust performance and outperform the conventional PIC and the iterative frequency domain decision feedback equalizer (FD-DFE) systems over multipath fading channel environment.