Eosinophil cationic protein/RNase 3 is another RNase A-family ribonuclease with direct antiviral activity
Abstract
Eosinophil cationic protein (ECP) is one of two RNase A-superfamily ribonucleases found in secretory granules of human eosinophilic leukocytes. Although the physiologic function of eosinophils [and thus of the two eosinophil ribonucleases, ECP and eosinophil-derived neurotoxin (EDN)] remains controv …
Keywords
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
humans
pubmed abstract
nih
national institutes of health
national library of medicine
research support
non-u.s. gov't
electrophoresis
recombinant proteins / pharmacology
antiviral agents / pharmacology*
j b domachowske
h f rosenberg
eosinophil granule proteins
ribonucleases*
respiratory syncytial viruses / drug effects
blood proteins / metabolism*
k d dyer
ribonuclease
glycosylation
polyacrylamide gel
pmid:9649619
pmc147714
doi:10.1093/nar/26.14.3358
blood proteins / pharmacology
recombinant proteins / metabolism
pancreatic / metabolism*
pancreatic / pharmacology
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120793
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