COVID-19: Loss of bridging between innate and adaptive immunity?

COVID-19: Loss of bridging between innate and adaptive immunity?

Rao, Vishal U S;Arakeri, Gururaj;Subash, Anand;Rao, Jyothsna;Jadhav, Sachin;Suhail Sayeed, Mufti;Rao, Gururaj;Brennan, Peter A;
medical hypotheses 2020 Vol. 144 pp. 109861
242
rao2020covid19medical

Abstract

COVID-19 has spread to most countries in the world. However, there are some striking differences in how COVID-19 is behaving in different age groups. While data on COVID-19 is limited, children appear to be less susceptible to severe disease. These unique characteristics may be considered as a potential link to understanding the immune system and response in COVID-19 and lead to an effective cure to the disease. We suggest a possible role of loss of bridging between innate and adaptive immunity in COVID-19 and a potential treatment modality also discussed.

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